The most common disorders associated with the endocrine gland are diabetes mellitus acromegaly, Addison’s disease, Cushing’s syndrome, Grave’s disease, Hashimoto’s thyroiditis, hyperthyroidism, hypothyroidism, and prolactinoma. The endocrine system disorders occur due to an imbalance in the endocrine glands that produce the hormones. Acromegaly is caused due to the overproduction of the growth hormone. Prolactimia is caused due to the overproduction of the prolactin hormone. Addison’s disease and Cushing’s syndrome are caused due to imbalance in the hormones produced by the adrenal glands. Diabetes mellitus and other autoimmune diseases are caused due to genetic factors. Hyperthyroidism, hypothyroidism, and Hashimoto’s diseases are caused due to fluctuations in the thyroid hormone. Tumors in the thyroid gland may also cause endocrine disorders.
Endocrine Glands
Endocrine glands are glands that release chemical substances known as hormones into the bloodstream. These hormones flow with the bloodstream and reach the target cell and make significant changes. The endocrine glands, nervous system, and immune system work together to cope up with stressful events. The endocrine system plays a major role in growth, repair, digestion, homeostasis, and sexual reproduction. The hormones released into the bloodstream reach the target cell and release a cascade of signaling pathways that causes changes in the cell. The body’s main endocrine glands are the pituitary gland, thyroid gland, parathyroid gland, adrenal gland, pancreas, ovaries, and testes.
Pituitary Gland – The pituitary gland is the gland that is present in the brain; it helps in regulating the hormones produced by different glands of the body. It is connected to the nervous system through the hypothalamus. The hormones released by the pituitary gland are the gonadotropin-releasing hormone, growth hormone, adrenocorticotropic hormone, prolactin, antidiuretic hormone, thyroid-stimulating hormone, and oxytocin.
Thyroid gland – The thyroid gland is present at the front of the food pipe. It is a butterfly-shaped organ that releases the T3 and T4 thyroid hormones required for the metabolism and maintenance of homeostasis in the body. It also controls the production of TSH from the pituitary gland.
Parathyroid Gland – parathyroid gland is located just beside the thyroid gland. It takes part in calcium, phosphate, and vitamin D regulation.
Adrenal Glands – Adrenal glands are two glands that are situated right on top of each kidney. The adrenal gland can be categorized into two parts. These are the adrenal cortex as well as adrenal medulla. The adrenal cortex can be described as the outer portion of the adrenal gland. The adrenal medulla can be referred to as the inner portion of the adrenal gland. Adrenal cortex releases cortisol, aldosterone, and sex hormones. The adrenal medulla secretes adrenaline that is required for flight and fright response.
Pancreas – Pancreas is the organ that is present in the abdomen; it aids indigestion. The pancreas also secretes insulin that controls the amount of sugar in the bloodstream. The pancreas makes additional hormones such as glucagon and somatostatin.
Ovaries – Ovaries are located in the pelvis of females. Ovaries are responsible for the secretion of female sex hormones estrogen and progesterone. The estrogen and progesterone levels fluctuate between menarche, menopause, and during different phases of the menstrual cycle. The ovaries also produce the male hormone testosterone but in small quantities.
Testes – Testes are present in the scrotal sac of males. The main function of testes is to secrete the testosterone hormone. The testosterone is secreted by the Leydig cells that are located between the seminiferous tubules
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