The blood capillaries are categorized into three different types:
Continuous capillary: These capillaries are said to be continuous as the lining of endothelial is continuous without any interruptions and they permit the transport of only smaller molecules through the intercellular cleft. The smaller molecules may include water and ions and other lipid-soluble molecules. These capillaries are subdivided into two categories: one which has several transport vesicles and is seen in fingers, skin, skeletal muscles, and gonads. Second, are the ones that have very few vesicles and are seen in the central nervous system.
Fenestrated capillaries: Fenestrated capillaries are the ones that have the endothelial cells with pores. These capillaries are about 60-80 nm in diameter and are called fenestrated. Such capillaries allow the diffusion of a specified amount of protein and other small molecules. They tend to carry a diaphragm which is oriented by fibrils. Fenestrated capillaries are majorly found in the intestines, glomeruli, pancreas, and endocrine glands.
Sinusoidal capillaries: Sinusoidal capillaries can also be termed as discontinuous capillaries due to wider openings in the endothelium. The capillaries are a kind of open-pore capillary and can also be called a sinusoid. The openings are about 30 to 40 micrometers in diameter. In the case of sinusoidal capillaries, the openings are not covered with the diaphragm whereas in fenestrated capillaries these openings were covered with the diaphragm. Sinusoids permit the transport of RBCs, WBCs, and proteins
which are majorly seen in the spleen, bone marrow, circumventricular organs, and liver.
Impacts Due to Bad Functioning of Capillaries
Port-wine stains: These are kind of stains or a mark happened due to the enlarging of the capillaries. These marks are visible on the skin from birth itself and are visible in pink or red color. These days do not require any treatment as they don’t spread to other parts of the body.
Petechiae: It is a condition in which the capillaries tend to leak the blood into the skin and results in the formation of round spots. The symptoms of the same may include scurvy, leukemia, scarlet fever, trauma, and a low level of platelets.
Arteriovenous malformation syndrome: It is a kind of syndrome in which an abnormal tangle occurs between arteries and veins. This tangle can be found in any area in the body, but are mainly observed in the brain and spinal cord. The symptoms of this may include weakness, headache, and aproblem in vision or speech.
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