It controls the blood levels of amino acid homocysteine by combining with other nutrients, vitamin B6 and B12.
Increased levels of homocysteine indicate the sign of heart attack. Conversely, low levels of folic acid are a common cause. Folic acid deficiency is caused by overconsumption of alcohol, celiac disease, and inflammatory bowel disease (IBD).
Certain medications may also cause the reduction of folic acid.
Deficiency of folic acid may restrict growth, inflammation of the tongue, loss of appetite, breathlessness, diarrhea, irritation, forgetting quickly, mental disorder, and gingivitis.
Folic acid is highly required for pregnant women to avoid neural tube congenital disabilities, cleft palate, spina bifida, and damaged brain.
Sources of folate are broccoli, brussels sprouts, green leafy vegetables, peas, chickpeas, cereals. The liver is recommended not to include during the pregnancy period.
Antacids and Its Role in the Body
Antacids help reduce heartburn, indigestion, gastro-esophageal reflux disease (GORD), gastritis, and ulcers. Although long-term medications are not recommended, they are helpful for a short period to relieve inflammation and uneasiness.
Antacids should be taken before gastritis symptoms and sometimes before going to sleep or after eating.
Heartburn or indigestion occurs after eating food. Therefore, intake of antacids is suggested after eating food to avoid the problem.
No other medications must be consumed for 3-4 hours after consuming antacids as they react with other medicines.
Antacids can be consumed with alcohol, but alcohol can alter the symptoms and makes it worse.
Side-effects of antacids are constipation, diarrhea, cramps, and vomiting. These symptoms reduce as the intake of the antacid stop.
Not all individuals are allowed to consume antacids, such as pregnant women must take suggestions from the doctor before taking them.
For children under 12 years old and with heart, kidney, and liver disease, individuals with high and low blood sugar levels other medications as antacids react entirely and reduce their absorption.
Relation between Folate and Antacids
Antacids react with folate and reduce its absorption entirely in the body. Therefore, it must be clarified with the doctor if any other medications are being followed.
Antibiotics such as tetracycline interfere with folic acid consumption at the same time. Therefore, it reduces its absorption and effectiveness. Therefore, the combination of folic acid and B vitamins must be consumed with a time gap before or after consuming tetracycline.
Birth control medications, cholesterol-lowering medications – anticonvulsants for seizures, medications for birth control, colestipol, bile acid sequestrants as medications for lowering cholesterol decrease the folic acid levels in the blood and reduce the body’s capacity to use it as a vitamin.
Methotrexate reduces the levels of folic acid in the body. Its use is to treat cancer, rheumatoid arthritis (RA), and psoriasis. A higher dose of folic acid prescribes when methotrexate consumes for RA and psoriasis. However, when consumed for cancer, the consumption of folic acid must be neglected because it reacts with the medication and shows the effect on cancer.
Omeprazole and ranitidine reduce or inhibit the absorption of folic acid entirely in the body.
Various antacids need to be consumed after being prescribed by the doctor as they are reactive to vitamins such as folate.
The absorption of folate in the body is decreased by the reactivity of the antacid, which makes the body deficient in vitamins.
It is suggested to consume folate supplements or foods after 2 hours of consuming antacids which may help to stop their reactivity and side effects.
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